Professor
Saptarshi Majumdar
A-611
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PhD: Ph.D, IIT Kharagpur
Research Interests: Polymers, Ion interactions, Biomaterials, Molecular dynamics, Industrial Processes
“Biomaterials & charged Polymers – A complicated domain with interesting dynamics and applications.”
Research Overview
Our focus on Poly-Nano-Bio group, is developing cross-linker free biomaterials and understanding the physicochemical aspects of ionic interactions with charged polymers. The chemically modified polymer biomaterials may result in toxicity and issues with biocompatibility and FDA approvals. Hence, we focus on the physical interactions of polymers to develop biomaterials for different applications. We also emphasis on developing certain theories on charged polymers. Our group actively worked with Tata Steel to develop laboratory demonstrations for several products from low-cost tailing coals.
Research Highlights
Physicochemical aspects of polyelectrolytes and polyampholytes
Biomaterials are prepared using chemically crosslinked polymers to increase their dissolution resistance which in turn induce toxicity. Main emphasis is given to the interactions of the charged polymers to get the desired cross-linker free biomaterials without hampering the biocompatibility.
Interaction perspective of biomaterial development
The biomaterials are usually developed using the trial-and error method and without a scientific knowledge of interactions. The main aim is to study the interactions of polymers and other components and design a better biomaterial showing superior results.
Ionic interactions of polymers
The theories of polymer physics are more aligned towards the neutral polymers. We aim to develop certain theories by studying the ionic interaction (salts, acids) with charged polymers and an applications of these in biomaterial development.
Tailing Coal to Value Added Products
Several projects are successfully completed with Tata Steel in last few years to convert waste to wealth i.e., low-cost tailing coal to value added products like C-slurry (as fuel), Activated-C and Battery Grade electrode materials.
Associated Projects
Ongoing
Analysis on Dynamic Light Scattering (DLS) Equipment (No. of measurements-02 No)
Start Year: 2025
Sponsor: PROTEIN ADVANCED ANALYTICS PRIVATE LIMITED
Ongoing
CLEANZ CoE
Start Year: 2024
Sponsor: COAL INDIA LIMITED
Co-PI: Dr. Raja Banerjee Dr. Chandra Shekhar Sharma
Ongoing
Testing equipment name: IREMF/IITH/CHEMICAL/DSC DIFFERENTIAL SCANNNG CALORIMETRY Facility incharge: Prof. Saptarshi Majumdar
Start Year: 2024
Sponsor:
Ongoing
Investigation on the biophysical factors regulating the phase transition mechanisms for assembly and disassembly of stress granules
Start Year: 2023
Sponsor: DBT
Ongoing
Analysis on Dynamic Light Scattering (DLS) Equipment (No. of measurements-01 No)
Start Year: 2023
Sponsor: LABINDIA INSTRUMENTS PRIVATE LIMITED
Completed
Feasibility study for the production of Hierarchical carbon Nano Materials from Tailing coal and coal tar
Start Year: 2019
Sponsor: Tata Steel limited
Ongoing
Analysis on Gel Permeation Chromatography(GPC) Equipment (No. of measurements-06 Nos)
Start Year: 2022
Sponsor: ARAGEN LIFE SCIENCES PRIVATE LIMITED
Completed
Process Development for Generation of Coal Related Products from High Ash Trailings Coal
Start Year: 2018
Sponsor: Tata Steel Limited
Completed
Comprehensive Analysis of Existing Separation Processes of Coke Making by-products and Development of Value Added Products from Coal and Coal tar
Start Year: 2016
Sponsor: TATA Steel Ltd
Ongoing
Experimental & Simulation studies for Multiscale design of Non-crosslinked polymeric drug delivery vehicle for controlled drug release application : In search of ideal low-cost biomaterials
Start Year: 2021
Sponsor: SERB
Co-PI: Dr. Debaprasad Shee
Selected Publications
Multifunctional NiO-curcumin nanocomposite-loaded scaffolds for bone regeneration and antibacterial activity
L K Sellappan; S Mishra; S Sundaresan; T Rathinavelan; S Majumdar
Competitive effects of anion mobility and viscous forces on interactions of hyaluronic acid and alginic acid with Hofmeister salts
Sougat Das; Saptarshi Majumdar
Formulation and In Vitro Assessment of a Hybrid Gel-Microparticle Composite for Ocular Delivery of Dual-Antiglaucoma Drugs
S K Panigrahi; D Saha; S Das; S Majumdar; L Giri
Single cell resolution imaging techniques in optic nerve models in vivo and in vitro
D Saha; R K Gupta; I Kaur; S Majumdar; L Giri
Journal: Proteomics & Systems Biology (Book Chapter)Year: 2025DOI: 10.1016/B978-0-443-15580-2.00005-9
Fabrication of crosslinker free hydrogels with diverse properties: An interplay of multiscale physical forces within polymer matrix
Tithi Basu; Debasish Goswami; Saptarshi Majumdar
Interaction-Based Perspective for Designing Polymer Biomaterial: A Strategic Approach to the Chitosan-Glycerophosphate System
Sougat Das; Lopamudra Giri; Saptarshi Majumdar
An Experimentally Derived Prediction Model for Diffusion and Electrostatically Controlled Physical Interactions of Polyampholytes and Salts
Sougat Das; Saptarshi Majumdar
Elucidating the influence of electrostatic force on the re-arrangement of H-bonds of protein polymers in the presence of salts
Tithi Basu; Sougat Das; Saptarshi Majumdar
Molecular interactions of acids and salts with polyampholytes
Sougat Das; Tithi Basu; Saptarshi Majumdar
Unveiling the potentials of hydrophilic and hydrophobic polymers in microparticle systems: Opportunities and challenges in processing techniques
Subrat Kumar Panigrahi; Sougat Das; Saptarshi Majumdar